Brain injuries like stroke can be debilitating and require time-sensitive treatment. Clotting factors like thrombin are commonly administered to patients, but there are many other stroke-related signs that can be targeted, such as swelling and ion imbalances in the surrounding fluids. New research shows that brain fluids can be normalized with adrenergic receptor antagonists, a combination of drugs to block the activity of (nor)adrenaline in the brain. This experimental treatment for stroke aided motor recovery and reduced cell death in mice, as reported in the Proceedings of the National Academy of Sciences on May 13.
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